Hayden Panettiere’s recent passing has been classified as accidental, with the Greenville County Coroner’s Office attributing it to the “toxic effects” of a combination of drugs, including fentanyl.
The actress, recognized for her performances in television series such as Heroes and Nashville, passed away on August 16 at a residence in Greenville, South Carolina where she had been residing.
Emergency personnel discovered Panettiere in cardiac arrest upon their arrival and were unable to revive her, as stated by the coroner’s office.
After a collaborative investigation between the coroner’s office and the Greenville City Police Department, it was confirmed in an official statement to CBC News on Tuesday that “the cause of death has been determined to be the toxic effects of fentanyl, 4-ANPP, Alprazolam, Methocarbamol, and Quetiapine.”
Quetiapine is an antipsychotic drug prescribed for conditions like schizophrenia, bipolar disorder, and major depression, while Alprazolam is used to manage anxiety and panic disorders, including anxiety linked to depression.
Methocarbamol serves as a muscle relaxant, and 4-ANPP is a chemical associated with fentanyl production, a potent opioid.
Had recently been in treatment
The autopsy report noted “no signs of trauma that could have contributed to the death,” the statement indicated.
The Associated Press later reported that the coroner’s findings also indicated that Panettiere had recently been discharged from a rehabilitation center in Malibu, California, only weeks prior to her death.
The actress, who passed away just days shy of her 37th birthday, had been open about her struggles with fame, addiction, and mental health, including postpartum depression after giving birth to her daughter in 2014.
Panettiere candidly shared her experiences through interviews and in her latest memoir, This Is Me: A Reckoning.
Her passing sparked an outpouring of tributes and memories from fans and colleagues alike.
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Neutrogena responds after Hayden Panettiere fans renew call for boycott
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COMMOTION
Why are people mad at Neutrogena on behalf of Hayden Panettiere?
It also reignited previous backlash against skincare brand Neutrogena, for which Panettiere had served as a global ambassador and spokesperson for nearly ten years before the birth of her daughter.
She had claimed that the company severed ties with her after she began to openly discuss her experiences with postpartum depression.


