Doctors are cautioning about a resurgence of a severe vitamin deficiency condition linked to the widespread use of proton pump inhibitors (PPIs) in the UK. The Sir Charles Gairdner Hospital in Western Australia highlighted the risk of scurvy, a potentially fatal condition, associated with PPIs like omeprazole.
Scurvy, if left untreated, can lead to organ failure, significant internal bleeding, infections, and ultimately, death. It was infamous for claiming the lives of numerous sailors in history due to the lack of fresh fruits and vegetables during extended sea journeys.
Approximately 15% of the UK population consumes PPIs, with England alone accounting for 73 million doses annually, equivalent to 6% of all prescriptions issued. A recent report in the British Medical Journal Case Reports revealed that PPIs hinder the absorption of vitamin C in the body, potentially triggering scurvy. The study documented a case of a middle-aged man who developed scurvy after PPI use.
The initial symptom observed was a red-brown pinpoint rash that originated on his legs and spread to his hands and arms. Blood tests indicated a severe deficiency in vitamin C and low levels of other essential nutrients. The patient received daily doses of vitamin C, vitamin D3, folic acid, and multivitamins, leading to a full recovery.
The individual had also been neglecting meals, lacking consumption of fruits and vegetables, and recently underwent stomach surgery for weight loss. Following the vitamin supplementation regimen, the rash disappeared, and his vitamin C levels normalized.
Dr. Andrew Dermawan from Sir Charles Gairdner Hospital emphasized the growing concern of malnutrition post-stomach surgery and the financial constraints hindering access to nutritious food amidst the current cost of living crisis.
PPIs are commonly prescribed for indigestion and stomach ulcers to protect the stomach from the adverse effects of other medications and are available over the counter.
Scurvy results from a deficiency in vitamin C, vital for collagen production that maintains healthy skin, blood vessels, and connective tissue. Inadequate vitamin C intake impairs the body’s ability to repair itself, leading to various symptoms.
Symptoms of scurvy manifest after prolonged insufficient dietary vitamin C intake, typically over several months, and can be alleviated with vitamin C supplements or by consuming vitamin C-rich foods.
Prompt treatment with vitamin C supplements or dietary adjustments can significantly improve symptoms in a matter of days to weeks. However, if left untreated for an extended period, scurvy can result in severe complications or fatal outcomes.